Globin 2 Globins 2 Inner cavities 2 Ligand migration 2 Ligands 2 Protein Conformation 2 Protein dynamics 2 Structure-Activity Relationship 2 Structure–function relationships amino acid sequence 2 association constant 2 binding affinity 2 carboxyhemoglobin 2 chemistry 2 crystal structure 2 disulfide 2 disulfide bond 2 globin 2 hemoglobin 2 human 2 hydrogen bond 2 ligand 2 ligand binding 2 molecular dynamics 2 myoglobin 2 neuroglobin 2 nonhuman 2 plasticity 2 protein conformation 2 protein function 2