3T3 cell line 2 A549 cell line 2 Article 2 Cucurbitaceae 2 K ras protein MTT assay 2 Raf protein 2 STAT3 protein 2 actin filament 2 animal experiment 2 animal model 2 antineoplastic activity 2 apoptosis 2 bitter taste 2 cell cycle G2 phase 2 cell cycle M phase 2 cell cycle arrest 2 cucurbitacin 2 cytotoxicity 2 epidermal growth factor receptor 2 genetic transcription 2 lung cancer 2 lung tumor 2 mitogen activated protein kinase 2 mouse 2 nonhuman 2 phosphatidylinositol 3 kinase 2 protein kinase B 2 signal transduction 2 transgenic mouse 2