Amino acid interactions 2 Association reactions 2 Atomistic molecular dynamics simulations 2 Binding Sites 2 Binding sites 2 Calcium 2 Calcium concentration 2 Calcium distributions 2 Connexin Connexins 2 DFNA3 protein, human 2 Deafness 2 Electron density profiles 2 Genes 2 Humans 2 Lipid Bilayers 2 Lipid bilayers 2 Molecular Dynamics Simulation 2 Molecular dynamics 2 Mutation 2 POPC 2 Variant annotation 2 binding site 2 calcium 2 chemistry 2 gap junction protein 2 genetics 2 hearing impairment 2 human 2 lipid bilayer 2