Article mouse nonhuman 120 controlled study 114 Animals 106 animal 106 metabolism 98 genetics 96 Mice 84 animal experiment 80 priority journal 80 animal cell 66 male 56 animal tissue 52 human 48 Humans 46 animal model 46 gene expression 46 Male 44 female 42 protein expression 42 unclassified drug 42 drug effects 38 gene expression regulation 36 messenger RNA 36 pathology 34 physiology 32 Female 30 down regulation 26 protein function 26