ADAMTS13 A4085T 3 APOPTOSIS 3 CUB-2 DOMAIN 3 D1362V MISSENSE MUTATION 3 DOMINIO CUB-2 3 ESTRADIOL 3 HISTAMINA 3 HISTAMINE 3 MUTACION DE SENTIDO ERRONEO D1362V 3 MUTAGENESIS SITIO-DIRIGIDA 3 PROGESTERONA 3 PROGESTERONE 3 PROLIFERACION 3 PROLIFERATION 3 SITE-DIRECTED MUTAGENESIS 3 TESTOSTERONA 3 TESTOSTERONE 3 VWF 3