article priority journal unclassified drug nonhuman 916 controlled study 760 Animals 556 animal cell 368 Humans 302 human 282 protein expression 250 Mice 238 mouse 224 animal experiment 194 human cell 182 animal tissue 174 protein function 166 enzyme activity 164 Molecular Sequence Data 146 male 146 rat 144 female 142 Rats 140 Male 138 Female 134 Protein Binding 116 Trypanosoma cruzi 116 metabolism 116 nucleotide sequence 114 Amino Acid Sequence 110 animal model 104