animal cell controlled study nonhuman unclassified drug article 432 Animals 416 priority journal 388 mouse 262 Mice 216 Humans 178 animal experiment 176 protein expression 176 human 172 animal 158 metabolism 134 female 126 human cell 126 Article 118 animal tissue 116 male 116 animal model 104 rat 104 Rats 96 Female 92 antiviral activity 92 Male 90 in vitro study 82 signal transduction 82 Cercopithecus aethiops 78 messenger RNA 78