human unclassified drug Humans 280 controlled study 226 nonhuman 224 priority journal 215 article 200 human cell 192 Animals 178 metabolism 111 protein expression 108 Article 97 animal cell 89 animal 87 mouse 78 Mice 69 chemistry 68 in vitro study 64 protein function 63 female 58 animal experiment 53 Cell Line, Tumor 52 Female 52 signal transduction 52 Cell Line 50 drug effects 48 Male 47 male 47 cell proliferation 46 genetics 46