nonhuman protein function unclassified drug priority journal 164 controlled study 150 article 140 Animals 139 protein expression 119 human 90 Humans 85 animal cell 79 metabolism 78 mouse 78 Mice 62 animal experiment 59 animal 58 genetics 52 Article 50 protein analysis 46 signal transduction 46 protein protein interaction 44 Female 39 animal tissue 36 Signal Transduction 35 animal model 35 protein localization 35 protein binding 34 enzyme activity 33 gene expression 30 female 29