mouse unclassified drug nonhuman 409 controlled study 350 Animals 320 Mice 298 article 287 priority journal 281 animal cell 280 animal experiment 225 animal model 167 human 166 animal 154 Humans 148 protein expression 140 animal tissue 138 metabolism 123 female 119 male 114 human cell 109 Article 104 Female 103 Male 90 protein function 82 Mice, Inbred BALB C 80 signal transduction 69 messenger RNA 67 genetics 66 in vitro study 65 cell proliferation 57