mouse nonhuman unclassified drug controlled study 346 Animals 313 Mice 291 article 282 animal cell 280 priority journal 276 animal experiment 223 animal model 167 human 159 animal 147 Humans 141 animal tissue 138 protein expression 138 female 119 metabolism 116 male 114 human cell 105 Female 103 Article 102 Male 90 Mice, Inbred BALB C 80 protein function 78 signal transduction 67 in vitro study 63 messenger RNA 63 genetics 62 gene expression 57