Article mouse unclassified drug nonhuman 102 controlled study 96 Animals 80 animal 78 animal experiment 74 priority journal 70 animal cell 68 Mice 66 metabolism 64 human 50 protein expression 48 animal model 46 animal tissue 46 male 42 Humans 40 drug effects 34 human cell 34 genetics 32 female 30 protein function 30 in vivo study 28 signal transduction 28 in vitro study 26 messenger RNA 26 Male 22 gene expression 22 embryo 20