animal experiment metabolism nonhuman physiology controlled study 149 Animals 148 animal 148 animal tissue 93 priority journal 91 Article 90 male 84 mouse 81 Male 70 Mice 61 article 61 female 58 animal model 52 animal cell 50 Female 46 unclassified drug 45 drug effect 39 rat 35 protein expression 34 drug effects 32 signal transduction 32 C57BL mouse 31 Mice, Inbred C57BL 31 adult 31 genetics 31 hippocampus 31