metabolism nonhuman animal 838 Animals 809 controlled study 802 priority journal 658 Article 596 article 478 animal cell 424 genetics 420 unclassified drug 412 animal experiment 386 mouse 372 physiology 365 human 331 animal tissue 315 Humans 308 Mice 308 female 281 chemistry 274 male 258 protein expression 257 Female 225 Male 218 drug effects 215 enzyme activity 207 signal transduction 199 drug effect 197 animal model 169 rat 167