Humans human 743 metabolism controlled study 382 Animals 359 animal 359 priority journal 335 nonhuman 308 genetics 288 article 279 human cell 261 Article 258 unclassified drug 226 chemistry 223 female 201 physiology 188 protein expression 188 Female 178 signal transduction 173 mouse 153 animal cell 139 pathology 134 Mice 131 drug effects 128 male 109 in vitro study 108 protein function 108 cell line 107 Signal Transduction 106 cell proliferation 105