Article metabolism nonhuman 596 controlled study 592 Animals 444 animal 444 priority journal 420 unclassified drug 288 genetics 276 human 274 Humans 258 animal experiment 236 drug effects 224 animal cell 210 mouse 208 chemistry 204 female 204 physiology 198 animal tissue 196 male 184 protein expression 184 Female 166 Mice 160 Male 154 human cell 148 enzyme activity 136 signal transduction 130 in vitro study 122 pathology 112 gene expression 106