male metabolism Male 422 animal 393 Animals 347 controlled study 258 nonhuman 258 article 227 female 214 animal experiment 193 priority journal 188 Article 184 physiology 179 Female 176 mouse 151 animal tissue 144 genetics 130 Mice 123 human 121 drug effects 113 Humans 109 adult 104 animal cell 104 rat 90 drug effect 85 protein expression 82 unclassified drug 79 Rats 78 in vitro study 77 pathology 71