animal controlled study male Animals 351 nonhuman 345 Male 301 animal experiment 238 Article 234 metabolism 217 priority journal 215 physiology 182 female 181 animal tissue 172 mouse 141 Female 131 animal cell 127 adult 122 Mice 119 article 117 drug effects 111 genetics 104 animal model 83 protein expression 79 human 78 Humans 72 unclassified drug 70 drug effect 66 pathology 57 in vitro study 53 immunohistochemistry 50