chemistry human Humans 388 metabolism 229 animal 199 Animals 197 article 170 controlled study 154 nonhuman 154 unclassified drug 147 priority journal 130 Article 118 genetics 96 human cell 93 drug effects 68 chemical structure 62 molecular dynamics 60 physiology 58 drug effect 57 in vitro study 57 protein binding 55 mouse 53 structure activity relation 51 female 50 synthesis 50 Mice 47 animal cell 47 cell line 45 protein conformation 43 Cell Line 42