controlled study nonhuman article 197 Animals 137 priority journal 136 animal cell 88 mouse 74 Mice 70 unclassified drug 64 animal experiment 59 protein expression 51 male 49 Male 44 animal tissue 40 Humans 38 animal 36 female 36 metabolism 34 Female 33 animal model 32 Rats 29 protein function 29 rat 28 human 25 signal transduction 25 Animalia 24 physiology 24 gene expression 23 genetics 23 messenger RNA 23