controlled study mouse nonhuman 1,220 Animals 981 Mice 940 article 907 priority journal 897 animal experiment 796 animal cell 712 animal model 599 animal tissue 539 male 454 female 453 protein expression 397 animal 392 Female 379 unclassified drug 350 Male 348 metabolism 319 human 315 Article 306 Humans 300 Mice, Inbred BALB C 236 human cell 207 signal transduction 203 cell proliferation 191 enzyme activity 189 in vitro study 181 Mice, Inbred C57BL 168 in vivo study 162