controlled study metabolism protein expression nonhuman 219 Animals 203 animal 199 priority journal 184 Article 164 human 151 Humans 146 animal cell 142 genetics 132 article 127 mouse 126 unclassified drug 119 female 117 animal experiment 115 Mice 112 Female 103 human cell 95 drug effects 85 physiology 81 animal tissue 80 signal transduction 78 male 77 cytology 75 Male 73 Western blotting 68 cell line 68 protein function 68