controlled study female metabolism nonhuman animal 222 Animals 220 Female 184 animal experiment 155 priority journal 149 Article 138 animal cell 134 animal tissue 126 mouse 120 Mice 106 male 95 animal model 89 article 88 genetics 83 physiology 81 protein expression 81 drug effects 75 unclassified drug 72 Male 69 human 69 Humans 65 adult 61 pathology 61 cytology 52 in vitro study 52 in vivo study 45