adult controlled study metabolism Article 98 female 96 nonhuman 89 Animals 87 animal 87 male 85 priority journal 84 Female 80 Male 69 human 62 animal experiment 61 Humans 58 physiology 49 animal tissue 46 drug effects 46 genetics 46 protein expression 44 animal cell 42 Adult 39 mouse 35 pathology 34 Mice 31 unclassified drug 30 article 28 gene expression 26 in vitro study 24 Water Pollutants, Chemical 22