article controlled study nonhuman 1,594 priority journal 1,368 Animals 1,022 animal experiment 648 male 602 animal cell 594 female 593 human 584 unclassified drug 517 Humans 514 Female 502 Male 484 animal tissue 456 mouse 416 Mice 382 protein expression 344 rat 339 human cell 320 animal model 309 Rats 288 enzyme activity 287 Animalia 224 adult 200 metabolism 189 animal 178 signal transduction 167 in vitro study 162 Argentina 158