animal cell controlled study nonhuman 112 signal transduction priority journal 97 Animals 92 article 83 mouse 65 Mice 56 Signal Transduction 49 protein expression 45 animal 43 animal experiment 43 animal tissue 40 metabolism 40 human 39 Humans 37 female 37 unclassified drug 37 animal model 32 human cell 30 Female 28 rat 28 Article 27 cell proliferation 27 male 26 enzyme activation 24 Rats 23 messenger RNA 22 genetics 21