Animals animal tissue controlled study male nonhuman 451 Male 370 animal experiment 342 priority journal 337 article 333 mouse 202 Mice 192 animal 172 animal cell 164 female 162 animal model 160 metabolism 128 rat 121 Article 120 protein expression 116 Female 114 Rats 109 physiology 98 unclassified drug 80 enzyme activity 79 messenger RNA 71 Rats, Sprague-Dawley 69 drug effects 67 immunohistochemistry 65 adult 61 drug effect 59