chemistry metabolism priority journal nonhuman 151 controlled study 123 animal 106 Animals 102 Article 98 unclassified drug 98 Humans 94 human 94 article 91 genetics 75 enzymology 47 molecular dynamics 46 animal cell 43 protein conformation 43 protein binding 41 protein domain 41 binding site 36 enzyme activity 36 signal transduction 36 Protein Conformation 34 in vitro study 34 physiology 34 amino acid sequence 33 female 32 protein expression 32 protein protein interaction 32 Protein Binding 31