article protein function unclassified drug priority journal 146 controlled study 142 nonhuman 140 Animals 113 protein expression 102 human 75 Humans 67 animal cell 54 mouse 52 Mice 50 metabolism 50 protein analysis 49 human cell 48 animal experiment 39 enzyme activity 38 genetics 37 protein localization 37 protein protein interaction 36 Protein Binding 33 Cell Line 32 Female 31 messenger RNA 31 signal transduction 31 animal 30 animal tissue 30 animal model 29 protein binding 29