article human 291 human cell unclassified drug Humans 238 controlled study 233 priority journal 164 nonhuman 158 Animals 134 animal cell 100 protein expression 86 Cell Line, Tumor 85 Mice 72 mouse 71 Cell Line 70 protein function 48 in vitro study 47 cell proliferation 44 drug structure 44 metabolism 40 female 39 Protein Binding 38 signal transduction 38 cancer cell culture 37 Cercopithecus aethiops 36 apoptosis 35 animal experiment 33 cytotoxicity 33 protein protein interaction 33 cell line 32