article drug synthesis unclassified drug nonhuman 94 drug structure 83 controlled study 66 Animals 62 Structure-Activity Relationship 48 priority journal 48 structure activity relation 43 Humans 42 drug screening 38 Trypanosoma cruzi 34 human 34 human cell 30 IC 50 28 proton nuclear magnetic resonance 28 stereochemistry 28 Molecular Structure 26 animal cell 26 drug activity 26 enzyme inhibition 26 antiviral activity 24 Drug Design 22 Magnetic Resonance Spectroscopy 22 chemical reaction 22 in vitro study 22 reaction analysis 22 synthesis 22 Cercopithecus aethiops 20