animal animal tissue metabolism nonhuman 299 Animals 295 controlled study 274 animal experiment 204 priority journal 197 Article 194 mouse 152 physiology 140 male 138 female 132 animal cell 126 Mice 124 Male 108 Female 104 article 103 unclassified drug 96 genetics 94 animal model 89 drug effects 89 protein expression 78 immunohistochemistry 65 drug effect 61 messenger RNA 61 pathology 61 gene expression 56 rat 56 enzyme activity 51