animal model animal tissue controlled study mouse nonhuman animal experiment 319 Animals 262 Mice 260 priority journal 241 article 231 female 170 animal cell 165 male 160 protein expression 125 Female 120 Male 110 animal 102 Article 98 human 86 Humans 83 Mice, Inbred BALB C 81 metabolism 81 unclassified drug 78 cell proliferation 70 Mice, Inbred C57BL 62 in vivo study 59 in vitro study 58 enzyme activity 57 signal transduction 51 pathology 50