animal experiment controlled study enzyme activity nonhuman article 203 Animals 189 priority journal 186 animal tissue 180 animal model 129 male 128 mouse 125 rat 98 Mice 88 female 87 Male 81 Rats 78 protein expression 78 Female 75 metabolism 73 animal cell 72 animal 66 unclassified drug 62 Article 58 Animalia 55 oxidative stress 52 Liver 50 Rats, Wistar 40 Oxidative Stress 37 enzyme inhibition 35 superoxide dismutase 34