Animals 83 animal animal experiment animal model male nonhuman 83 controlled study 81 Male 73 mouse 67 Mice 63 Article 60 metabolism 60 priority journal 57 animal tissue 43 animal cell 39 drug effects 38 pathology 36 genetics 34 human 32 Humans 30 physiology 28 protein expression 28 adult 24 female 24 article 23 in vitro study 20 in vivo study 20 unclassified drug 19 cell proliferation 18 human cell 18