aged controlled study female human adult 137 male 137 article 123 Female 113 priority journal 110 Humans 107 Male 103 Aged 99 Middle Aged 87 Adult 73 major clinical study 66 clinical article 62 middle aged 28 Argentina 26 human cell 25 Adolescent 24 Article 24 adolescent 24 clinical trial 24 protein expression 21 human tissue 19 Aged, 80 and over 18 controlled clinical trial 18 Alzheimer disease 16 Treatment Outcome 16 depression 16