Male animal model nonhuman 310 animal experiment 295 Animals 292 controlled study 277 male 260 article 248 priority journal 219 mouse 202 Mice 201 animal tissue 167 animal cell 121 Female 91 Rats 85 protein expression 83 rat 83 female 82 animal 75 unclassified drug 62 Humans 60 Article 54 human 54 metabolism 52 in vivo study 45 Animalia 44 enzyme activity 44 drug effect 43 in vitro study 41 oxidative stress 41