Humans unclassified drug human 603 nonhuman 457 article 449 controlled study 441 priority journal 430 Animals 418 human cell 325 metabolism 226 protein expression 214 animal cell 190 animal 173 Mice 161 mouse 148 Article 146 chemistry 143 protein function 129 signal transduction 117 Cell Line, Tumor 115 Cell Line 114 in vitro study 110 Female 108 genetics 96 cell proliferation 95 animal experiment 94 female 93 drug effects 90 Male 86 Protein Binding 84