Humans chemistry human 143 unclassified drug metabolism 102 controlled study 99 nonhuman 91 Animals 84 animal 84 human cell 64 priority journal 63 Article 62 article 57 drug effects 44 in vitro study 41 animal cell 37 genetics 32 structure activity relation 31 mouse 29 protein expression 29 synthesis 28 chemical structure 27 drug structure 27 cell line 26 cell proliferation 26 molecular dynamics 26 Mice 25 Cell Line 23 protein function 23 drug effect 22