Humans controlled study protein function human 136 article 116 priority journal 110 human cell 100 nonhuman 85 Animals 84 protein expression 83 unclassified drug 74 metabolism 62 animal cell 57 mouse 56 Mice 54 genetics 54 animal 42 Cell Line 41 Female 38 animal experiment 38 signal transduction 38 Cell Line, Tumor 36 protein protein interaction 36 Article 34 female 34 cell proliferation 31 messenger RNA 29 animal model 28 protein analysis 27 regulatory mechanism 27