Humans controlled study male human 442 Male 434 female 364 Female 339 article 337 adult 309 priority journal 301 Adult 229 Middle Aged 176 nonhuman 145 Animals 138 human cell 130 Article 123 major clinical study 113 aged 109 clinical article 105 Aged 103 animal experiment 96 protein expression 83 Young Adult 75 animal cell 75 metabolism 73 animal 72 physiology 72 Argentina 71 mouse 71 Mice 69