Humans chemistry human 388 metabolism 223 Animals 191 animal 191 article 166 controlled study 150 nonhuman 146 unclassified drug 143 priority journal 124 Article 110 genetics 92 human cell 89 drug effects 66 chemical structure 60 drug effect 57 molecular dynamics 56 physiology 56 in vitro study 53 mouse 53 protein binding 53 female 50 Mice 47 animal cell 47 synthesis 46 structure activity relation 45 cell line 43 Models, Molecular 42 cell proliferation 41