Humans article cyclization cytotoxicity drug synthesis unclassified drug 1 hydroxy 10 methyl 9(10h) acridone 2 1,3 dihydroxy 5 methoxyacridone 2 10 allyl 6 chloro 4 methoxy 9(10h) acridone 2 10 allyl 6 chloro 9(10h) acridone 2 2 fluoro 5 methoxy n (pyridine 3 yl)acridone 4 carboxamide 2 2 hydroxy 5 methoxy 3 (3 methylbut 2 enyl)naphthalene 1,4 dione (5 methoxylapachol) 2 2 hydroxy 7 methoxynaphthalene 1,4 dione (2 hydroxy 7 methoxy 1,4 naphthoquinone 2 3 allyloxy 7 methoxy 1 hydroxyacridone 2 3 hydroxy 6 methoxy 2 (3 methylbut 2 en 1 yl)naphthalene 1,4 dione (7 methoxylapachol) 2 3,4 dihydro 10 hydroxy 2,2 dimethyl 2h benzo[g]chromene 5,6 dione (10 hydroxy beta lapachone) 2 3,4 dihydro 10 methoxy 2,2 dimethyl 2h benzo[g]chromene 5,6 dione (10 methoxy beta lapachone) 2 3,4 dihydro 6 hydroxy 2,2 dimethyl 2h benzo[g]chromene 5,10 dione (6 hydroxy alpha lapachone) 2 3,4 dihydro 6 hydroxy 2,2 dimethyl 2h benzo[g]chromene 5,10 dione (6 methoxy alpha lapachone) 2 3,4 dihydro 7 hydroxy 2,2 dimethyl 2h benzo[g]chromene 5,6 dione (7 hydroxy beta lapachone) 2 3,4 dihydro 7 methoxy 2,2 dimethyl 2h benzo[h]chromene 5,6 dione (7 methoxy beta lapachone) 2 3,4 dihydro 8 hydroxy 2,2 dimethyl 2h benzo[h]chromene 5,6 dione (8 hydroxy beta lapachone) 2 3,4 dihydro 8 methoxy 2,2 dimethyl 2h benzo[g]chromene 5,10 dione (8 methoxy alpha lapachone) 2 3,4 dihydro 8 methoxy 2,2 dimethyl 2h benzo[h]chromene 5,6 dione (8 methoxy beta lapachone) 2 3,4 dihydro 9 hydroxy 2,2 dimethyl 2h benzo[g]chromene 5,10 dione (9 hydroxy alpha lapachone) 2 3,4,5,6 tetrahydro 2,2 dimethyl 5,6 dioxo 2h benzo[h]chromen 7 yl pivalate (7 pivaloyl beta lapachone) 2 3,7 dimethoxy 1 hydroxyacridone 2 5 chloro 1,3 dihydroxyacridone 2 7 amino 1,3 dihydroxy 10 methyl 6 [4 (2 pyridinyl) 1 piperazinyl] 9(10h) acridone 2 7 amino 1,3 dimethoxy 10 methyl 6 [4 (4 thiazol) 1 piperazinyl] 9(10h) acridone 2