Humans Structure-Activity Relationship chemistry controlled study 4 drug effect drug structure human 4 metabolism 4 nonhuman 4 structure activity relation 4 unclassified drug 11beta,17beta dihydroxy 6 methyl 17alpha (1 propynyl)androsta 1,4,6 trien 3 one 2 2 [2 carboxy 1 (2 nitrophenyl)ethyl] 1,3 dioxoisoindoline 5 carboxylic acid 2 2 [2 carboxy 1 (4 ethylphenyl)ethyl] 1,3 dioxoisoindoline 5 carboxylic acid 2 2 [2 carboxy 1 (4 hydroxyphenyl)ethyl] 1,3 dioxoisoindoline 5 carboxylic acid 2 2 [2 carboxy 1 (4 methoxyphenyl)ethyl] 1,3 dioxoisoindoline 5 carboxylic acid 2 2 [2 carboxy 1 (4 nitrophenyl)ethyl] 1,3 dioxoisoindoline 5 carboxylic acid 2 2 [2 carboxy 1 (4 tolyl)ethyl] 1,3 dioxoisoindoline 5 carboxylic acid 2 3 (1,3 dioxoisoindolin 2 yl) 3 (4 ethylphenyl)propanoic acid 2 3 (1,3 dioxoisoindolin 2 yl) 3 (4 hydroxyphenyl)propanoic acid 2 3 (1,3 dioxoisoindolin 2 yl) 3 (4 methoxyphenyl)propanoic acid 2 3 (1,3 dioxoisoindolin 2 yl) 3 (4 nitrophenyl)propanoic acid 2 3 (1,3 dioxoisoindolin 2 yl) 3 (4 tolyl)propanoic acid 2 3 (4 ethylphenyl) 3 (5 methyl 1,3 dioxoisoindolin 2 yl)propanoic acid 2 3 (4 hydroxyphenyl) 3 (5 methyl 1,3 dioxoisoindolin 2 yl)propanoic acid 2 3 (4 methoxyphenyl) 3 (5 methyl 1,3 dioxoisoindolin 2 yl)propanoic acid 2 3 (5 methyl 1,3 dioxoisoindolin 2 yl) 3 (4 nitrophenyl)propanoic acid 2 3 (5 methyl 1,3 dioxoisoindolin 2 yl) 3 (4 tolyl)propanoic acid 2 3 (5 methyl 1,3 dioxoisoindolin 2 yl) 3 (naphthalen 2 yl)propanoic acid 2 3 amino 3 (4 ethylphenyl)propanoic acid 2