Animals animal human nonhuman Humans 409 metabolism 264 controlled study 244 priority journal 204 Article 190 mouse 173 animal cell 168 unclassified drug 160 genetics 151 Mice 149 physiology 148 article 136 female 133 animal experiment 132 human cell 114 Female 111 chemistry 107 protein expression 102 animal model 91 male 90 pathology 86 Review 82 drug effects 82 Male 76 signal transduction 74 adult 69