Animals animal controlled study nonhuman 918 metabolism 643 Article 580 priority journal 529 animal experiment 474 animal cell 430 physiology 399 mouse 392 article 388 female 362 male 351 animal tissue 348 Mice 342 Male 299 genetics 299 Female 292 unclassified drug 288 human 279 Humans 260 drug effects 249 protein expression 224 animal model 205 drug effect 197 chemistry 182 adult 161 in vitro study 150 pathology 139