article controlled study protein expression nonhuman 613 priority journal 598 Animals 518 animal cell 364 animal experiment 308 mouse 293 Mice 285 human 276 Humans 273 animal tissue 248 female 241 unclassified drug 232 human cell 226 Female 222 male 199 animal model 183 Male 171 protein function 170 rat 162 Rats 144 cell proliferation 137 messenger RNA 137 signal transduction 137 enzyme activity 133 metabolism 127 apoptosis 117 Western blotting 109