gene deletion 52 article 47 nonhuman 38 priority journal 38 controlled study 37 human 24 Humans 23 metabolism 23 genetics 21 Gene Deletion 19 unclassified drug 19 Mutation 14 female 14 Animals 13 Female 13 gene mutation 13 Article 12 animal cell 12 enzyme activity 12 Male 11 male 11 phenotype 11 promoter region 11 Sequence Deletion 10 adult 10 mouse 10 physiology 10 Mice 9 nucleotide sequence 9 signal transduction 9