priority journal unclassified drug article 553 nonhuman 539 controlled study 423 Animals 318 human 215 animal cell 206 Humans 199 protein expression 152 metabolism 135 Article 134 mouse 130 animal experiment 121 Mice 116 animal tissue 103 human cell 102 enzyme activity 98 animal 97 protein function 94 female 92 male 91 Female 80 Male 80 rat 77 signal transduction 75 in vitro study 71 chemistry 69 Rats 68 Molecular Sequence Data 67