controlled study human male priority journal article 146 female 142 Male 138 Humans 134 adult 120 Female 109 Adult 75 Middle Aged 61 aged 56 human cell 56 major clinical study 53 clinical article 50 nonhuman 49 Aged 43 Article 37 Animals 34 animal cell 34 protein expression 34 animal experiment 30 mouse 28 Argentina 23 Mice 21 animal model 21 middle aged 21 unclassified drug 21 Adolescent 20